Newport Beach MedSpa GLP Medical Weight Loss Injections
Peptide therapy with GLP-1 medications, such as semaglutide and tirzepatide, are weekly injections that mimic a natural hormone to reduce appetite.
You’ve cut back, worked out, and tried every plan, yet the scale still won’t budge. You’re not alone. Hunger and cravings often push back harder as you lose weight, which makes progress hard to sustain. GLP-1 medications help quiet that pushback, so your healthy habits finally have room to work.
At Newport Beach MedSpa, we offer GLP-1 medical weight loss to patients across Orange County. We welcome patients from Newport Beach, Costa Mesa, Irvine, Corona Del Mar, Laguna Beach, and beyond.
Our program goes beyond a prescription. We start with a complimentary consultation, review your labs, and scan your body composition. From there, we build a semaglutide or tirzepatide plan around your body, your goals, and your health history. Then we stay with you through weekly or monthly check-ins, adjusting your dose as you progress.
Many of our patients pair GLP-1 treatment with CoolSculpting® or SmartLipo® to target stubborn fat in specific areas. GLP-1s help you lose weight overall, while these treatments remove fat cells where you want to see change.
What Is Weight Loss?
Weight loss is a drop in your overall body weight, which can come from fat, water, and muscle. When you lose fat, your fat cells shrink, but they don’t disappear. In adults, the number of fat cells stays fairly stable, even after significant weight loss. Those smaller fat cells can expand again if the weight returns, and some areas may hold on to stubborn fat even as the scale goes down.
What Is Fat Reduction?
Fat reduction removes fat cells from a specific area instead of shrinking them. Once treated fat cells are eliminated, they don’t come back. The fat cells that remain can still grow with weight gain, so a stable weight helps you keep your results.
We offer two fat reduction options. CoolSculpting freezes and eliminates fat cells without surgery. SmartLipo uses laser-assisted liposuction to remove fat and tighten skin. Many of our patients combine fat reduction with GLP-1 treatment, so their results show up in the areas that matter most to them.
How Do GLP-1 Medications Lead to Weight Loss?
GLP-1 stands for glucagon-like peptide-1, a hormone your gut releases after you eat. It signals fullness to your brain, slows digestion, and helps regulate blood sugar. GLP-1 medications mimic this hormone, so many patients feel satisfied with smaller portions and notice fewer cravings.
Because you feel full sooner and stay full longer, eating less feels easier. Over time, that steady drop in calories leads to weight loss. First developed to treat type 2 diabetes, these medications are now widely used for weight management.
What Is the Difference Between Semaglutide and Tirzepatide?
Both medications work on the GLP-1 pathway. The difference comes down to how many hormone receptors each one targets.
Semaglutide
Semaglutide mimics GLP-1 alone. It’s a once-weekly injection that helps reduce appetite and cravings, so smaller portions feel more satisfying. Your provider starts you on a low dose and increases it in steps as your body adjusts.
Tirzepatide
Tirzepatide targets two receptors: GLP-1 and GIP, another gut hormone involved in appetite and blood sugar. Like semaglutide, it’s a once-weekly injection, and your dose increases in steps over time. Your provider may recommend it based on your goals and health history.
Both medications can support meaningful weight loss, and individual results vary. During your consultation, our team explains how each medication fits your goals, health history, and budget.
How Does CoolSculpting Complement GLP-1 Weight Loss?
With 10,000+ CoolSculpting treatments performed, our team has extensive experience planning fat reduction around your goals. CoolSculpting is an FDA-cleared, non-invasive treatment that uses controlled cooling to target fat cells. Treated fat cells break down while your skin stays intact, and your body clears them naturally over the following weeks.
In clinical studies, one treatment reduced fat in the treated area by up to 25%. CoolSculpting is not a weight loss treatment. It works best on pinchable fat in areas like the abdomen, flanks, thighs, and under the chin.
That makes it a natural partner to GLP-1 therapy. As your overall weight comes down, CoolSculpting can refine the areas that hold on to fat. We help you decide when to add it, whether during your GLP-1 program or as you near your goal.
How Does SmartLipo Remove Stubborn Fat?
SmartLipo is a minimally invasive, laser-assisted liposuction procedure. It targets fat that diet, exercise, and GLP-1 medications may not reach. A thin laser fiber heats and softens fat through a small incision, and the fat is then suctioned away. The laser’s heat also stimulates collagen, which can help tighten skin in the treated area.
Compared to traditional liposuction, laser-assisted liposuction is linked to faster recovery, less discomfort, and improved skin tightening. It works best for small to moderate areas, like the abdomen, flanks, arms, thighs, and under the chin.
After GLP-1 weight loss, SmartLipo can remove remaining pockets of fat. It can also help firm loose skin in those same areas.
What Does Our Medical Weight Management Program Include?
Our GLP-1 program is a comprehensive medical weight management plan, not a stand-alone injection. Here is what your care includes:
- A complimentary consultation and personalized treatment plan
- Lab work review or a lab order
- A body composition scan
- Individualized dosing
- Weekly or monthly check-ins
Your Consultation and Personalized Treatment Plan
Every program starts with a complimentary consultation. We review your health history, current medications, past weight loss efforts, and goals. Together, we decide whether semaglutide or tirzepatide fits you best and map out a realistic plan. We also discuss how your face and skin may change as you lose weight.
Lab Work Before You Start
Lab work gives us a clear picture of your metabolic health before your first injection. We review your recent results or provide a lab order if you need new testing. These results help us choose a safe starting dose and track your progress over time.
Body Composition Scan
A body composition scan measures far more than the number on the scale. It shows your muscle mass, body fat, and how each one changes throughout treatment.
Many of our patients learn they have lower muscle mass than expected at their first scan. That insight shapes our protein and calcium recommendations, so you lose fat while protecting strength.
Dosing Designed for You
Your dose is designed for you, not pulled from a one-size-fits-all chart. We start low and increase gradually, which helps many patients manage side effects like nausea. Every dose change is guided by our medical team and your progress, not guesswork.
Weekly or Monthly Check-Ins
We follow you with weekly or monthly check-ins, depending on your plan and where you are in treatment. Each visit lets us track your weight, review side effects, and adjust your dose when needed. This steady follow-up keeps you accountable and gives you a team to lean on.
Why Does Medical Supervision Matter on a GLP-1?
GLP-1 medications are now easy to find online, often without labs, scans, or follow-up care. A medically supervised program adds safeguards that help protect your health and your results.
- Muscle protection: Weight lost on a GLP-1 is not all fat. In some studies, lean mass made up as much as 40% of total weight lost. Regular body scans help us spot muscle loss early.
- Side effect management: Digestive side effects are the most common, and many are mild to moderate during dose increases. Gradual dosing and regular check-ins help many patients stay comfortable.
- Long-term results: In one study, adults who stopped semaglutide regained about two-thirds of their lost weight within a year. We plan for maintenance from the start, with habits that support lasting results.
Am I a Candidate for GLP-1 Weight Loss?
GLP-1 medical weight loss may be a good fit if you:
- Have a BMI of 30 or higher
- Have a BMI of 27 or higher with a weight-related condition, like high blood pressure or high cholesterol
- Have tried diet and exercise without lasting results
- Want medical guidance instead of managing medication on your own
These BMI ranges match the FDA’s weight management criteria for GLP-1 medications. GLP-1 treatment is not right for everyone, including some patients with a history of pancreatitis. Our team reviews your full health history to confirm treatment is safe for you.
How Much Do Semaglutide and Tirzepatide Cost?
Your cost depends on your medication and dose. Each price below includes four injections, along with your consultation, lab work, body scan, and check-ins. Your provider recommends a dose based on your labs and progress.
Semaglutide Pricing
- 0.25 mg: $249
- 0.5 mg: $299
- 1.0 mg: $349
Tirzepatide Pricing
- 2 mg: $399
- 4 mg: $499
- 7 mg: $599
Higher doses are also available. Our team will share pricing during your consultation.
Wellness Add-Ons
Wellness injections start at $35, and IV therapy starts at $99. Some patients add them to their plan for extra support during treatment.
Membership Savings
Our memberships add another layer of savings. Signature and Premier members save on GLP-1 management. Beauty Bank credit can also go toward GLP-1 program and medication charges. Credits are subject to the final Newport Beach MedSpa Membership Agreement.
Will My Face and Body Change as I Lose Weight?
As the weight comes off, you may notice changes in your face and skin. Fat loss may leave cheeks and temples looking hollow, and skin may feel looser than before. We talk through these changes during your consultation so we can plan ahead together.
- Ultherapy® uses focused ultrasound energy to stimulate collagen and lift skin on the face, neck, and chest.
- RF microneedling pairs fine needles with radiofrequency energy to help firm skin and refine texture.
- Dermal fillers can restore lost facial volume. The right product depends on your facial balance and goals.
- CoolTone® can help strengthen and tone muscles in the abdomen, buttocks, and thighs.
Your provider recommends treatments based on your individual assessment and goals.
Why Choose Our Team for Medical Weight Loss?
For 20+ years, our team has helped patients feel confident through personalized, medically guided care. We treat weight loss as a medical partnership, not a transaction.
Our professional staff includes physician assistants, nurse practitioners, registered nurses, and medical assistants. They bring many years of experience in body treatments and weight management, including hormone assessment.
You work with this team at every stage, from your first scan to your maintenance plan. We also offer fat reduction, skin tightening, and muscle toning treatments to support your results beyond the scale.
Frequently Asked Questions About GLP-1 Weight Loss
Start Your GLP-1 Weight Loss Plan
Ready to lose weight with a medical team in your corner? Patients come to us from Newport Beach, Costa Mesa, Irvine, Corona Del Mar, Laguna Beach, and across Orange County.
Book a Complimentary Consultation to build your personalized GLP-1 plan.
- Spalding KL, Arner E, Westermark PO, et al. Dynamics of Fat Cell Turnover in Humans. Nature. 2008;453(7196):783-787. https://www.nature.com/articles/nature06902
- Collins L, Costello RA. Glucagon-Like Peptide-1 Receptor Agonists. In: StatPearls. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK551568/
- Jastreboff AM, Aronne LJ, Ahmad NN, et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022;387(3):205-216. https://www.nejm.org/doi/full/10.1056/NEJMoa2206038
- Krueger N, Mai SV, Luebberding S, Sadick NS. Cryolipolysis for Noninvasive Body Contouring: Clinical Efficacy and Patient Satisfaction. Clin Cosmet Investig Dermatol. 2014;7:201-205. https://pmc.ncbi.nlm.nih.gov/articles/PMC4079633/
- Manzano-Finol A, Parra-Pelosi H, Cubillos-Valencia G, et al. Laser-Assisted Lipolysis: A Promising Alternative to Traditional Liposuction. Aesthetic Plast Surg. 2025;49(19):5522-5531. https://pmc.ncbi.nlm.nih.gov/articles/PMC12594724/
- Neeland IJ, Linge J, Birkenfeld AL. Changes in Lean Body Mass with Glucagon-Like Peptide-1-Based Therapies and Mitigation Strategies. Diabetes Obes Metab. 2024;26(Suppl 4):16-27. https://pubmed.ncbi.nlm.nih.gov/38937282/
- Wilding JPH, Batterham RL, Davies M, et al. Weight Regain and Cardiometabolic Effects After Withdrawal of Semaglutide: The STEP 1 Trial Extension. Diabetes Obes Metab. 2022;24(8):1553-1564. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542252/
- U.S. Food and Drug Administration. FDA Approves New Medication for Chronic Weight Management. November 8, 2023. https://www.fda.gov/news-events/press-announcements/fda-approves-new-medication-chronic-weight-management
- Drug Topics. How GLP-1 Therapies Could Impact Bone Density, Muscle Loss. July 6, 2026. https://www.drugtopics.com/view/how-glp-1-therapies-could-impact-bone-density-muscle-loss